Beta fructan

Using fibers as feed components as an active tool in different physiological
approaches was found long time ago .The nutritional fibers that came from the
different type of plant origin can be considered as a new task for discovering and
reveling its secrets .The use of the fibers as digestive promoter and beneficial microbe enhancers are the most wide area of interest in these uses for the last dedicate.

Using the fibers as immune stimulant came out by discovering the immune stimulant
role of some yeast cell wall components like the mann and glucan fibers of bakery’s
yeast saccharomyces cerevisiae. the fructo oligosaccharide as one of the major plant
components (found in more than3000 kind of plants) was very interesting for our labs
and research workers to find out it's possible uses and, how to use them in a good
useful strategic way in the animal production sectors using the interesting information

and data we found in our labs the only disadvantage we found in the fructo oligosacc-
haride was the big polymer size that reaches 60· polymers in only one molecule so we focused on a very small functional polymer component beta fiuctan that we get it out from the FOS complex carrying the structure"1,2 and . 2,6 beta fructan.

The beta fructan is considered-a revolutionary component can be used to activate the
immune system of different animal species. Poultry, cattle, equine, canine and feline the
activity of the fructans as interleukin modulator and coordinator was very interesting
since this make the beta fructan much more active desirable component than the

glucan because of its small molecular size and no need to be digested to carry out

its function on the contrary to beta glucans.

The short chain fructan "vas very powerful and invasive with a very short time limit to start acting in between the cells. The short and small size invasive beta fructan which consists only from 5 suger polymers gave the beta fructan extra good feature for the veterinary use as an immune stimulant as an intrarmuscular injection usage.

The lethicin as a fatty acid cover that do both prolonged and good release as per the
intramuscular injection gives the extrapower that was noticed in the immune reaction
of the beta fiuctan its ability to elongate the time of interleukin 10 appearance the
2,6 and 1,2 combination in a specific ratio makes a good drug immune interaction

That can emerge and engaged with a good level in the site of inflammation during
the disease course particularly during the secretion of the acutephase inflammatory
and pro inflammatory Cytokines.

 The excellent intramuscular absorption in addition to a very good enteric absorption
adds a helpful way to ease the product usage as a multi rout administration product.

All the cellular components that starts to be activated and the interleukin 10
appearance retardation results in a very good titer of the different vaccines applied after the use of the beta fiuctan if it is used 24-48 hours before the vaccine application.

The interleukin 4 and 5 interaction mediates the transformation of the B cells to
plasma cells resulting in a very good translation of multivalent vaccine or giving more than one vaccine in the same source of water in the same time as per some intensive vaccine program in poultry farms.

Use and indication.

As an immune stimulant for animal species.

Dose.

Poultry

125 ml per ton life body weight

Cattle.

I ml /20 k.g life body weight
Horses and equine

1ml / 30 k.g life body weight

Sheep and goat

1ml/ 10k.g life body weight,

The intra mammary application 5 ml intra quarter after empting the quarter from milkor pus cells then deep intra mammary infusion in the teet tree application is applied.

Withdrawal.

o day

Calves

Into milk feeding 5 ml per calf prevention of salmonella, coli and gram negative

Infections:

Navel application

2ml /navel are directly.
Pet animal

0.5 ml/ k.g feline
0.25ml/k.g canine

Usage as defecate deodorizer and digestive enhancer

1 ml/ drinking water once week increasing the dose for feline 1.5 in recommended
N.B

Shake well before use.
Protect from direct sunlight
Kept in room temperature.

Beta fructan is a trade mark of Gencore & C